Get A Biography of Paul Berg:The Recombinant DNA Controversy PDF

By Errol C Friedberg

With a Foreword through Sydney Brenner (Nobel laureate in body structure or medication, 2002)

This biography info the lifetime of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's lifestyles from delivery, in 1926, to the current, with certain emphasis on his huge, immense clinical contributions, together with being the 1st to improve know-how that ended in gene cloning technology. In 1980, Berg got a Nobel Prize in chemistry for this work.

In addition to his contributions within the examine laboratory, Berg orchestrated and oversaw a historical assembly at Asilomar, California that based on a threatening controversy surrounding the notion by means of many of the destructive power of recombinant DNA know-how. This assembly did a lot to prevent this controversy and to install position the law of recombinant DNA paintings, hence placing fears to rest.

The recombinant DNA controversy used to be a old end result of the invention of gene cloning. significantly, it represented a paramount instance of medical foresight and due diligence by way of the clinical neighborhood, instead of by means of regulatory entities within the usa and plenty of different nations. the last word recognition of gene/DNA cloning ended in a brand new period of contemporary biology that prospers to the present.

This publication is aimed basically at scientists and people in education. The booklet strives to easily supply details for the final reader, yet isn't in particular adapted for a common studying audience.

While many books conceal the recombinant DNA controversy, none have satisfactorily addressed this ancient interval and are usually contradictory concerning the many who is, where's, and why's concerned. also, the good majority of those have been written by way of non-scientists. This biography of Paul Berg offers entry to varied archived letters and files at Stanford collage no longer formerly addressed, and to the chronology of occasions as recalled and documented by way of him, in addition to different key personalities, a lot of whom have been interviewed.

Contents:

  • Part I:
    • Growing Up in Brooklyn
    • The crucial Paul Berg
    • College — and global battle II
    • Western Reserve University
    • Copenhagen
  • Part II:
    • Washington college, St. Louis
    • Discovering move RNA
    • Stanford college — and Its Refurbished division of Biochemistry
    • Transcription and Translation: New Directions
  • Part III:
    • Making Recombinant DNA — the 1st Faltering Steps
    • Making Recombinant DNA — an immense Breakthrough
    • EcoRI restrict Endonuclease — an immense Breakthrough
    • “Coincidence is the notice We Use after we cannot See the Levers and Pulleys”
    • Yet one other Stanford Contribution
  • Part IV:
    • An old assembly in Hawaii
    • The Recombinant DNA Controversy
    • A Momentous Gordon learn Conference
    • Making Recombinant Molecules with Frog DNA
    • The Controversy Heats Up
    • Asilomar II
    • The Dissenters: a distinct element of View
    • The Aftermath
    • Legislative and Revisionist demanding situations to Recombinant DNA
    • Asilomar II — classes Learned
  • Part V:
    • The Nobel Prize in Chemistry
    • Commercializing the Technology
    • Life is going on
    • The “Retirement” Years
    • Public coverage matters — and different Interests
    • Personal Challenges

Readership: Researchers, graduate scholars, undergraduates in lifestyles sciences, medication and chemistry and lay public.

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A Biography of Paul Berg:The Recombinant DNA Controversy Revisited by Errol C Friedberg


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